Yang Yang

Yang Yang,

Associate Professor

Department: PHHP-COM BIOSTATISTICS
Business Phone: (352) 294-1933
Business Email: yangyang@ufl.edu

Research Profile

My primary research focuses on developing statistical methods for transmission dynamics of infectious diseases such as influenza, dengue, Ebola, COVID-19, HIV and cholera at both individual and population levels. These methods are designed to evaluate transmissibility of pathogens, efficacy of interventions, and effects of risk factors in various study settings. Examples are studies with case-ascertained follow-up, competing risks of infection from co-circulating pathogens or strains, and high-dimensional missing data. I developed methods for assessing vaccine or antiviral efficacy when there was only a small number of laboratory-tested specimens. I am also interested in modeling co-circulating of multiple pathogens with cross-reactivity, e.g., dengue viruses and enteroviruses, especially when the underlying exposure history is incompletely observed. In response to the ongoing COVID-19 pandemic, I have been engaged in multiple collaborative projects of analyzing contact-tracing data, case incidence data and lab-testing data. My long-term goals in methodological research are to integrate phylodynamics and AI methods into transmission modeling and to address surveillance bias.

Open Researcher and Contributor ID (ORCID)

0000-0003-0428-5480

Areas of Interest
  • Bayesian modeling
  • Disease Modeling
  • Spatial statistics
  • Statistical computing

Publications

2021
Daily self-regulation with biofeedback to improve stress and job satisfaction in a primary care clinic.
Journal of family medicine and primary care. 10(2):968-973 [DOI] 10.4103/jfmpc.jfmpc_1820_20. [PMID] 34041106.
2021
Etiological and epidemiological features of acute respiratory infections in China
Nature Communications. 12(1) [DOI] 10.1038/s41467-021-25120-6. [PMID] 34408158.
2021
Factors Associated With Dropout of Participants in an App-Based Child Injury Prevention Study: Secondary Data Analysis of a Cluster Randomized Controlled Trial
Journal of Medical Internet Research. 23(1) [DOI] 10.2196/21636. [PMID] 33512318.
2021
Factors Associated With Household Transmission of SARS-CoV-2: An Updated Systematic Review and Meta-analysis.
JAMA network open. 4(8) [DOI] 10.1001/jamanetworkopen.2021.22240. [PMID] 34448865.
2021
Mapping ticks and tick-borne pathogens in China
Nature Communications. 12 [DOI] 10.1038/s41467-021-21375-1.
2021
Platelet and White Cell Reactivity to Top-Load Intravenous Perfluorocarbon Infusion in Healthy Sheep.
The Journal of surgical research. 267:342-349 [DOI] 10.1016/j.jss.2021.05.044. [PMID] 34192613.
2021
Using simulated infectious disease outbreaks to inform site selection and sample size for individually randomized vaccine trials during an ongoing epidemic.
Clinical trials (London, England). 18(5):630-638 [DOI] 10.1177/17407745211028898. [PMID] 34218667.
2020
Campylobacter Colonization, Environmental Enteric Dysfunction, Stunting, and Associated Risk Factors Among Young Children in Rural Ethiopia: A Cross-Sectional Study From the Campylobacter Genomics and Environmental Enteric Dysfunction (CAGED) Project.
Frontiers in public health. 8 [DOI] 10.3389/fpubh.2020.615793. [PMID] 33553097.
2020
Household Transmission of SARS-CoV-2: A Systematic Review and Meta-analysis.
JAMA network open. 3(12) [DOI] 10.1001/jamanetworkopen.2020.31756. [PMID] 33315116.
2020
Meteorological conditions and nonpharmaceutical interventions jointly determined local transmissibility of COVID-19 in 41 Chinese cities: A retrospective observational study
The Lancet Regional Health – Western Pacific. 2 [DOI] 10.1016/j.lanwpc.2020.100020. [PMID] 34173597.
2020
Transmission of SARS-CoV-2 in Public Transportation Vehicles: A Case Study in Hunan Province, China
Open Forum Infectious Diseases. 7 [DOI] 10.1093/ofid/ofaa430. [PMID] 33123609.
2019
A Spatio-Temporal Modeling Framework for Surveillance Data of Multiple Infectious Pathogens with Small Laboratory Validation Sets.
Journal of the American Statistical Association. 114(528):1561-1573 [DOI] 10.1080/01621459.2019.1585250. [PMID] 31937981.
2019
Acute Respiratory Illness in Rural Haiti.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 81:176-183 [DOI] 10.1016/j.ijid.2019.02.003. [PMID] 30772468.
2019
An App-Based Intervention for Caregivers to Prevent Unintentional Injury Among Preschoolers: Cluster Randomized Controlled Trial
JMIR mHealth and uHealth. 7(8) [DOI] 10.2196/13519. [PMID] 31400105.
2019
Are Patients Frequently Readmitted to the Hospital Different from the Other Admitted Patients?
Journal of the American Board of Family Medicine : JABFM. 32(1):58-64 [DOI] 10.3122/jabfm.2019.01.180052. [PMID] 30610142.
2019
Effects of infection history on dengue virus infection and pathogenicity.
Nature communications. 10(1) [DOI] 10.1038/s41467-019-09193-y. [PMID] 30886145.
2019
Impact of Inpatient Consults by a Family Medicine Teaching Service.
Southern medical journal. 112(1):21-24 [DOI] 10.14423/SMJ.0000000000000911. [PMID] 30608626.
2019
Needs Analysis for a Parenting App to Prevent Unintentional Injury in Newborn Babies and Toddlers: Focus Group and Survey Study Among Chinese Caregivers
JMIR mHealth and uHealth. 7(4) [DOI] 10.2196/11957. [PMID] 31038465.
2019
Timing of treatment interruption among latently infected tuberculosis cases treated with a nine-month course of daily isoniazid: findings from a time to event analysis.
BMC public health. 19(1) [DOI] 10.1186/s12889-019-7524-4. [PMID] 31481046.
2018
Burnout and Resiliency Among Family Medicine Program Directors.
Family medicine. 50(2):106-112 [DOI] 10.22454/FamMed.2018.836595. [PMID] 29432625.
2018
Dependency of Vaccine Efficacy on Preexposure and Age: A Closer Look at a Tetravalent Dengue Vaccine.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 66(2):178-184 [DOI] 10.1093/cid/cix766. [PMID] 29020332.
2018
Reply to Aguiar and Stollenwerk.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 66(4) [DOI] 10.1093/cid/cix883. [PMID] 29088434.
2018
The role of benzathine penicillin G in predicting and preventing all-cause acute respiratory disease in military recruits: 1991-2017.
Epidemiology and infection. 146(14):1854-1860 [DOI] 10.1017/S0950268818001838. [PMID] 29974837.
2018
Transmissibility of Norovirus in Urban Versus Rural Households in a Large Community Outbreak in China.
Epidemiology (Cambridge, Mass.). 29(5):675-683 [DOI] 10.1097/EDE.0000000000000855. [PMID] 29847497.
2017
Controlling cholera in the Ouest Department of Haiti using oral vaccines.
PLoS neglected tropical diseases. 11(4) [DOI] 10.1371/journal.pntd.0005482. [PMID] 28410382.
2016
Cholera in Cameroon, 2000-2012: Spatial and Temporal Analysis at the Operational (Health District) and Sub Climate Levels.
PLoS neglected tropical diseases. 10(11) [DOI] 10.1371/journal.pntd.0005105. [PMID] 27855171.
2016
The epidemiology and transmissibility of Zika virus in Girardot and San Andres island, Colombia, September 2015 to January 2016.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 21(28) [DOI] 10.2807/1560-7917.ES.2016.21.28.30283. [PMID] 27452806.
2016
Transmissibility and Pathogenicity of Ebola Virus: A Systematic Review and Meta-analysis of Household Secondary Attack Rate and Asymptomatic Infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 62(10):1277-1286 [DOI] 10.1093/cid/ciw114. [PMID] 26932131.
2015
A National Assessment of the Epidemiology of Severe Fever with Thrombocytopenia Syndrome, China
Nature Scientific Report. 5 [DOI] 10.1038/srep09679. [PMID] 25902910.
2015
Cholera Transmission in Ouest Department of Haiti: Dynamic Modeling and the Future of the Epidemic.
PLoS neglected tropical diseases. 9(10) [DOI] 10.1371/journal.pntd.0004153. [PMID] 26488620.
2015
Emerging tick-borne infections in mainland China: an increasing public health threat.
The Lancet. Infectious diseases. 15(12):1467-1479 [DOI] 10.1016/S1473-3099(15)00177-2. [PMID] 26453241.
2015
Statistical monitoring of the hand, foot and mouth disease in China.
Biometrics. 71(3):841-50 [DOI] 10.1111/biom.12301. [PMID] 25832170.
2014
A pathway EM-algorithm for estimating vaccine efficacy with a non-monotone validation set.
Biometrics. 70(3):568-78 [DOI] 10.1111/biom.12173. [PMID] 24766139.
2014
Household Transmission of Vibrio cholerae in Bangladesh.
PLoS neglected tropical diseases. 8(11) [DOI] 10.1371/journal.pntd.0003314. [PMID] 25411971.
2014
School-located influenza vaccination reduces community risk for influenza and influenza-like illness emergency care visits.
PloS one. 9(12) [DOI] 10.1371/journal.pone.0114479. [PMID] 25489850.
2012
A hybrid EM and Monte Carlo EM algorithm and its application to analysis of transmission of infectious diseases.
Biometrics. 68(4):1238-49 [DOI] 10.1111/j.1541-0420.2012.01757.x. [PMID] 22506893.
2012
Resampling-based methods in single and multiple testing for equality of covariance/correlation matrices.
The international journal of biostatistics. 8(1) [DOI] 10.1515/1557-4679.1388. [PMID] 22740584.
An App-Based Intervention for Caregivers to Prevent Unintentional Injury Among Preschoolers: Cluster Randomized Controlled Trial (Preprint)
. [DOI] 10.2196/preprints.13519.
Factors Associated With Dropout of Participants in an App-Based Child Injury Prevention Study: Secondary Data Analysis of a Cluster Randomized Controlled Trial (Preprint)
. [DOI] 10.2196/preprints.21636.
Needs Analysis for a Parenting App to Prevent Unintentional Injury in Newborn Babies and Toddlers: Focus Group and Survey Study Among Chinese Caregivers (Preprint)
. [DOI] 10.2196/preprints.11957.

Grants

Aug 2021 ACTIVE
Targeted vaccination strategies for COVID-19: A mathematical modeling approach UFF F020981
Role: Co-Investigator
Funding: UF FOU via GOLDMAN SACHS PHILANTHROPY FUND
Jun 2021 ACTIVE
Targeted vaccination strategies for COVID-19: A mathematical modeling approach
Role: Co-Investigator
Funding: SCHWAB CHARITABLE via CONWAY FAMILY FOUNDATION
Sep 2020 ACTIVE
Mathematical and Statistical Methods for the Control of Global Infectious Disease Threats
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAID
Jul 2020 ACTIVE
RAPID: Technological Solutions for Monitoring the Spreading ofCOVID-19
Role: Principal Investigator
Funding: NATL SCIENCE FOU
Jun 2019 – May 2020
Yr.6 Methods of Evaluating Vaccine Efficacy
Role: Co-Investigator
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIAID
Nov 2018 ACTIVE
Exposure Assessment of Campylobacter Infections in Rural Ethiopia (EXCAM)
Role: Co-Investigator
Funding: GATES FOU, BILL & MELINDA
Aug 2018 – Jul 2021
Design and Analysis of Vaccine Trials for Emerging Infectious Disease Threats
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAID
Jul 2018 – Jun 2019
Center for Statistics and Quantitative Infectious Diseases (CSQUID): Research Project 1 – Modeling, Spacial, Statistics
Role: Co-Investigator
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIGMS
Jul 2018 – Jun 2019
Center for Statistics and Quantitative Infectious Diseases (CSQUID): Research Project 3 – Understanding Transmission with Integrated Genetic and Epidemiologic Inference
Role: Co-Investigator
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIGMS
Jul 2018 – Jun 2019
Center for Statistics and Quantitative Infectious Diseases (CSQUID): Software Development and Core Facilities
Role: Co-Investigator
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIGMS
Jun 2018 – May 2019
Yr.5 Methods of Evaluating Vaccine Efficacy
Role: Co-Investigator
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIAID
Jan 2018 – Dec 2020
Regression, Phylogenetics, and Study Design in Infectious Disease Epidemiology
Role: Principal Investigator
Funding: OHIO STATE UNIV via NATL INST OF HLTH NIAID
Nov 2017 ACTIVE
EQUIP – Strengthening smallholder livestock systems for the future
Role: Project Manager
Funding: GATES FOU, BILL & MELINDA
Jul 2017 – Jun 2018
Center for Statistics and Quantitative Infectious Diseases (CSQUID): Research Project 1 – Modeling, Spacial, Statistics
Role: Co-Investigator
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIGMS
Jul 2017 – Jun 2018
Center for Statistics and Quantitative Infectious Diseases (CSQUID): Research Project 3 – Understanding Transmission with Integrated Genetic and Epidemiologic Inference
Role: Co-Investigator
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIGMS
Jul 2017 – Jun 2018
CSQUID U54- Software Development_Yr.4
Role: Co-Investigator
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIGMS
Jun 2017 – May 2018
Methods of Evaluating Vaccine Efficacy_Yr.4
Role: Co-Investigator
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIAID
Jan 2017 ACTIVE
Dynamics of Influenza Transmission in Nicaraguan Households
Role: Project Manager
Funding: UNIV OF MICHIGAN ANN ARBOR via NATL INST OF HLTH NIAID
Dec 2016 ACTIVE
Cholera persistence, transmission, and clinical illness in Haiti
Role: Project Manager
Funding: NATL INST OF HLTH NIAID
Sep 2016 ACTIVE
Southeastern and Coastal Center for Agricultural Health and Safety (SCC-AHS)
Role: Co-Investigator
Funding: CTRS FOR DIS CNTRL INST OCCUP SFTY HLTH
Jul 2016 ACTIVE
Cholera transmission and evolution in Port-au-Prince, Haiti
Role: Project Manager
Funding: NATL INST OF HLTH NIAID
Jul 2016 – Jun 2017
Center for statistics and quantitative infectious disease (csquid): software development and core facilities
Role: Project Manager
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH
Jul 2016 – Jun 2017
center for statistics and quantitative infectious diseases (csquid): project 1 modeling , special, statistics
Role: Project Manager
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIGMS
Jul 2016 – Jun 2017
center for statistics and quantitative infectious diseases (csquid): research project 3 understanding transmission
Role: Project Manager
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIGMS
Jul 2015 – Jun 2016
Center for Statistics and Quantitative Infectious Diseases
Role: Project Manager
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIGMS
Jul 2015 – Jun 2016
Center for Statistics and Quantitative Infectious Diseases (CSQUID): Research Project 3 – Understanding Transmission with Integrated Genetic and Epidemiologic Inference
Role: Project Manager
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIGMS
Jul 2015 – Jun 2016
Center for Statistics and Quantitative Infectious Diseases (CSQUID): Software Development and Core Facilities
Role: Project Manager
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH NIGMS
Jun 2015 – May 2018
Spatio-Temporal Modeling for Surveillance Data of Multiple Pathogens
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAID
Jun 2015 – May 2017
Methods for evaluating vaccine efficacy
Role: Project Manager
Funding: FRED HUTCHINSON CANCER RES CTR via NATL INST OF HLTH

Education

M.S.
2004 · Emory University
Ph.D.
2004 · Emory University
B.S.
1998 · South China University of Technology

Teaching Profile

Courses Taught
2015-2021
PHC6092 Introduction to Biostatistical Theory
2014-2015,2017-2021
PHC7979 Advanced Research
2017,2019-2020
PHC6601 Seminar in Contemporary Public Health Issues
2017,2019-2020
PHC6946 Public Health Internship
2019
PHC6905 Independent Study
2018
STA7980 Research for Doctoral Dissertation
2015,2018-2021,2021
PHC7980 Research for Doctoral Dissertation
2013-2015
PHC7066 Large Sample Theory
2013
PHC6937 Spec Top Public Hlth

Contact Details

Phones:
Business:
(352) 294-1933
Emails:
Business:
yangyang@ufl.edu