Guogen Shan,
Professor
About Guogen Shan
We focus on developing new methods for clinical trials.
Software: Fisher’s exact approach for post hoc analysis of a chi-squared test Post hoc test, Fisher test, Exact test.
https://adaptivedesignstrial.shinyapps.io/posthoc/
Related Links:
Teaching Profile
Courses Taught
2021
GMS6827 Advanced Clinical Trial Methods
2023-2024
PHC7979 Advanced Research
2023-2024
PHC6937 Special Topics in Public Health
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0001-8690-6599
Areas of Interest
- Clinical Trials Design & Analysis
- Longitudinal Data Analysis
- Alzheimer’s Disease
- Cognitive Neuroscience
Publications
2024
ADSS: A Composite Score to Detect Disease Progression in Alzheimer’s Disease.
Journal of Alzheimer's disease reports.
8(1):307-316
[DOI] 10.3233/ADR-230043.
[PMID] 38405343.
2024
Association of Win-Loss Record With Neuropsychiatric Symptoms and Brain Health Among Professional Fighters.
The Journal of neuropsychiatry and clinical neurosciences.
36(2):118-124
[DOI] 10.1176/appi.neuropsych.20230108.
[PMID] 38258377.
2024
Comparison of Pocock and Simon’s covariate-adaptive randomization procedures in clinical trials.
BMC medical research methodology.
24(1)
[DOI] 10.1186/s12874-024-02151-3.
[PMID] 38273261.
2024
Confidence intervals for overall response rate difference in the sequential parallel comparison design
Statistical Papers.
[DOI] 10.1007/s00362-024-01606-5.
2024
Continuity corrected score confidence interval for the difference in proportions in paired data
Journal of Applied Statistics.
51(1):139-152
[DOI] 10.1080/02664763.2022.2118245.
[PMID] 38179158.
2024
Predicting Conversion Time from Mild Cognitive Impairment to Dementia with Interval-Censored Models.
Journal of Alzheimer's disease : JAD.
101(1):147-157
[DOI] 10.3233/JAD-240285.
[PMID] 39121117.
2024
Prior football or rugby exposure and white matter signal abnormalities in professional male mixed martial arts fighters.
The Physician and sportsmedicine.
1-5
[DOI] 10.1080/00913847.2024.2382085.
[PMID] 39022864.
2024
Rationale and Design for the BLOCK-SAH Study (Pterygopalatine Fossa Block as an Opioid-Sparing Treatment for Acute Headache in Aneurysmal Subarachnoid Hemorrhage): A Phase II, Multicenter, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial with a Sequential Parallel Comparison Design.
Neurocritical care.
[DOI] 10.1007/s12028-024-02078-z.
[PMID] 39138719.
2024
Score confidence interval with continuity correction for ratio of two independent proportions
METRON.
82(2):183-199
[DOI] 10.1007/s40300-023-00264-1.
2024
Statistical considerations when estimating time-saving treatment effects in Alzheimer’s disease clinical trials.
Alzheimer's & dementia : the journal of the Alzheimer's Association.
20(8):5421-5433
[DOI] 10.1002/alz.14035.
[PMID] 39030751.
2024
Two-stage response adaptive randomization designs for multi-arm trials with binary outcome
Journal of Biopharmaceutical Statistics.
34(4):526-538
[DOI] 10.1080/10543406.2023.2234028.
[PMID] 37452825.
2024
Validation of the Keele STarT MSK Tool for Patients With Musculoskeletal Pain in United States-based Outpatient Physical Therapy Settings.
The journal of pain.
25(7)
[DOI] 10.1016/j.jpain.2024.01.340.
[PMID] 38242334.
2023
A Research Protocol to Study the Priming Effects of Breathing Low Oxygen on Enhancing Training-Related Gains in Walking Function for Persons With Spinal Cord Injury: The BO2ST Trial.
Neurotrauma reports.
4(1):736-750
[DOI] 10.1089/neur.2023.0036.
[PMID] 38028272.
2023
Acute Headache Management for Patients with Subarachnoid Hemorrhage: An International Survey of Health Care Providers.
Neurocritical care.
38(2):395-406
[DOI] 10.1007/s12028-022-01571-7.
[PMID] 35915347.
2023
Blood biomarkers and neurodegeneration in individuals exposed to repetitive head impacts.
Alzheimer's research & therapy.
15(1)
[DOI] 10.1186/s13195-023-01310-w.
[PMID] 37828595.
2023
Continuity Corrected Wilson Interval for the Difference of Two Independent Proportions
Journal of Statistical Theory and Applications.
22(1-2):38-53
[DOI] 10.1007/s44199-023-00054-8.
[PMID] 37982044.
2023
New Confidence Intervals for Relative Risk of Two Correlated Proportions
Statistics in Biosciences.
15(1):1-30
[DOI] 10.1007/s12561-022-09345-7.
[PMID] 35615750.
2023
Promising zone two-stage design for a single-arm study with binary outcome
Statistical Methods in Medical Research.
32(6):1159-1168
[DOI] 10.1177/09622802231164737.
[PMID] 36998163.
2023
Response adaptive randomization design for a two-stage study with binary response
Journal of Biopharmaceutical Statistics.
33(5):575-585
[DOI] 10.1080/10543406.2023.2170399.
[PMID] 36735855.
2023
Sparring and the Brain: The Associations between Sparring and Regional Brain Volumes in Professional Mixed Martial Arts Fighters
Sports Medicine.
53(8):1641-1649
[DOI] 10.1007/s40279-023-01838-9.
2023
Traumatic encephalopathy syndrome: application of new criteria to a cohort exposed to repetitive head impacts.
British journal of sports medicine.
57(7):389-394
[DOI] 10.1136/bjsports-2022-105819.
[PMID] 36517216.
2022
Caffeine Enhances Intermittent Hypoxia-Induced Gains in Walking Function for People with Chronic Spinal Cord Injury.
Journal of neurotrauma.
39(23-24):1756-1763
[DOI] 10.1089/neu.2022.0120.
[PMID] 35686460.
2022
Conservative confidence intervals for the intraclass correlation coefficient for clustered binary data
Journal of Applied Statistics.
49(10):2535-2549
[DOI] 10.1080/02664763.2021.1910939.
[PMID] 35757040.
2022
Early vigabatrin augmenting GABA-ergic pathways in post-anoxic status epilepticus (VIGAB-STAT) phase IIa clinical trial study protocol.
Neurological research and practice.
4(1)
[DOI] 10.1186/s42466-022-00168-x.
[PMID] 35067230.
2022
Effects of dose change on the success of clinical trials
Contemporary Clinical Trials Communications.
30
[DOI] 10.1016/j.conctc.2022.100988.
[PMID] 36117568.
2022
Efficacy of Eravacycline Versus Best Previously Available Therapy for Adults With Pneumonia Due to Difficult-to-Treat Resistant (DTR) Acinetobacter baumannii.
The Annals of pharmacotherapy.
56(12):1299-1307
[DOI] 10.1177/10600280221085551.
[PMID] 35511209.
2022
Estimation of bias-corrected intraclass correlation coefficient for unbalanced clustered studies with continuous outcomes
Communications in Statistics – Simulation and Computation.
51(11):6691-6700
[DOI] 10.1080/03610918.2020.1811332.
2022
Evaluating the effects of a mindfulness mobile application on student pharmacists’ stress, burnout, and mindfulness.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
79(8):656-664
[DOI] 10.1093/ajhp/zxab467.
[PMID] 34864830.
2022
Monte Carlo cross-validation for a study with binary outcome and limited sample size.
BMC medical informatics and decision making.
22(1)
[DOI] 10.1186/s12911-022-02016-z.
[PMID] 36253749.
2022
Optimized Elastic Network Models With Direct Characterization of Inter-Residue Cooperativity for Protein Dynamics
IEEE/ACM Transactions on Computational Biology and Bioinformatics.
19(2):1064-1074
[DOI] 10.1109/tcbb.2020.3023147.
2022
Randomized two-stage optimal design for interval-censored data
Journal of Biopharmaceutical Statistics.
32(2):298-307
[DOI] 10.1080/10543406.2021.2009499.
[PMID] 34890525.
2022
Relationship between advanced pharmacy practice experience grading schemes and pharmacy residency match rates.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
79(24):2261-2270
[DOI] 10.1093/ajhp/zxac254.
[PMID] 36082956.
2021
Advanced statistical methods and designs for clinical trials for COVID-19.
International journal of antimicrobial agents.
57(1)
[DOI] 10.1016/j.ijantimicag.2020.106167.
[PMID] 33408032.
2021
Assessing Clinical Change in Individuals Exposed to Repetitive Head Impacts: The Repetitive Head Impact Composite Index
Frontiers in Neurology.
12
[DOI] 10.3389/fneur.2021.605318.
[PMID] 34295295.
2021
Bootstrap confidence intervals for correlation between continuous repeated measures
Statistical Methods & Applications.
[DOI] 10.1007/s10260-020-00555-1.
2021
Concussion occurrence and recognition in professional boxing and MMA matches: toward a concussion protocol in combat sports
The Physician and Sportsmedicine.
49(4):469-475
[DOI] 10.1080/00913847.2020.1856631.
2021
Economic and workload impact of therapeutic interchange of inhaler medications and nebulizer solutions.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.
78(1):41-48
[DOI] 10.1093/ajhp/zxaa343.
[PMID] 33103194.
2021
Effect of Weight Class on Regional Brain Volume, Cognition, and Other Neuropsychiatric Outcomes among Professional Fighters.
Neurotrauma reports.
2(1):169-179
[DOI] 10.1089/neur.2020.0057.
[PMID] 34223552.
2021
Machine learning methods to predict amyloid positivity using domain scores from cognitive tests
Scientific Reports.
11(1)
[DOI] 10.1038/s41598-021-83911-9.
[PMID] 33649452.
2021
Optimal two-stage designs based on restricted mean survival time for a single-arm study
Contemporary Clinical Trials Communications.
21
[DOI] 10.1016/j.conctc.2021.100732.
[PMID] 33553801.
2021
Partial Correlation Coefficient for a Study With Repeated Measurements
Statistics in Biopharmaceutical Research.
13(4):448-454
[DOI] 10.1080/19466315.2020.1784780.
[PMID] 35003527.
2021
Using the health belief model to assess the impact of student pharmacist-led health outreach events.
Currents in pharmacy teaching & learning.
13(6):694-698
[DOI] 10.1016/j.cptl.2021.01.031.
[PMID] 33867066.
2020
Accurate confidence intervals for proportion in studies with clustered binary outcome
Statistical Methods in Medical Research.
29(10):3006-3018
[DOI] 10.1177/0962280220913971.
2020
Accurate confidence intervals for risk difference in meta-analysis with rare events.
BMC medical research methodology.
20(1)
[DOI] 10.1186/s12874-020-00954-8.
[PMID] 32349702.
2020
Comments on “Exact inference for the random‐effect model for meta‐analyses with rare events”
Statistics in Medicine.
39(22):3022-3023
[DOI] 10.1002/sim.8500.
2020
Correlation Coefficients for a Study with Repeated Measures
Computational and Mathematical Methods in Medicine.
2020:1-11
[DOI] 10.1155/2020/7398324.
[PMID] 32300374.
2020
Evaluation of Guideline Recommendations for Dual Antipseudomonal Therapy in Hospitalized Adults with Pneumonia Using Combination Antibiograms.
Pharmacotherapy.
40(11):1089-1098
[DOI] 10.1002/phar.2466.
[PMID] 33037659.
2020
Exact confidence limits for proportion difference in clinical trials with bilateral outcome
Statistical Methods & Applications.
29(3):515-525
[DOI] 10.1007/s10260-019-00491-9.
2020
Exact Unconditional Tests for Dichotomous Data When Comparing Multiple Treatments With a Single Control
Therapeutic Innovation & Regulatory Science.
54(2):411-417
[DOI] 10.1007/s43441-019-00070-w.
2020
Letter to the Editor: A novel confidence interval for a single proportion in the presence of clustered binary outcome data (SMMR, 2019)
Statistical Methods in Medical Research.
29(2):636-637
[DOI] 10.1177/0962280219840056.
2020
Longitudinal change in regional brain volumes with exposure to repetitive head impacts.
Neurology.
94(3):e232-e240
[DOI] 10.1212/WNL.0000000000008817.
[PMID] 31871218.
2020
Sex Differences in Cognitive Changes in De Novo Parkinson’s Disease.
Journal of the International Neuropsychological Society : JINS.
26(2):241-249
[DOI] 10.1017/S1355617719001085.
[PMID] 31822306.
2020
Sex Moderates the Relationship That Number of Professional Fights Has With Cognition and Brain Volumes.
Frontiers in neurology.
11
[DOI] 10.3389/fneur.2020.574458.
[PMID] 33250844.
2020
The effect of age of first exposure to competitive fighting on cognitive and other neuropsychiatric symptoms and brain volume.
International review of psychiatry (Abingdon, England).
32(1):89-95
[DOI] 10.1080/09540261.2019.1665501.
[PMID] 31587599.
2020
The longitudinal associations between cognition, mood and striatal dopaminergic binding in Parkinson’s Disease.
Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition.
27(4):581-594
[DOI] 10.1080/13825585.2019.1653445.
[PMID] 31411534.
2020
The Relationship Between Fighting Style, Cognition, and Regional Brain Volume in Professional Combatants: A Preliminary Examination Using Brief Neurocognitive Measures.
The Journal of head trauma rehabilitation.
35(3):E280-E287
[DOI] 10.1097/HTR.0000000000000540.
[PMID] 31834060.
2020
Two-stage optimal designs based on exact variance for a single-arm trial with survival endpoints
Journal of Biopharmaceutical Statistics.
30(5):797-805
[DOI] 10.1080/10543406.2020.1730869.
[PMID] 32129130.
2019
Associations between Comorbid TDP-43, Lewy Body Pathology, and Neuropsychiatric Symptoms in Alzheimer’s Disease.
Journal of Alzheimer's disease : JAD.
69(4):953-961
[DOI] 10.3233/JAD-181285.
[PMID] 31127776.
2019
Efficient statistical inference for a parallel study with missing data by using an exact method.
Journal of biopharmaceutical statistics.
29(3):478-490
[DOI] 10.1080/10543406.2019.1605782.
[PMID] 31017028.
2019
Estimated Cardiorespiratory Fitness Is Associated With Reported Depression in College Students.
Frontiers in physiology.
10
[DOI] 10.3389/fphys.2019.01191.
[PMID] 31620016.
2019
Exact Unconditional Tests for Dichotomous Data When Comparing Multiple Treatments With a Single Control
Therapeutic Innovation & Regulatory Science.
[DOI] 10.1177/2168479018814697.
2019
Non-motor predictors of freezing of gait in Parkinson’s disease
Gait & Posture.
68:311-316
[DOI] 10.1016/j.gaitpost.2018.12.009.
[PMID] 30553992.
2019
Rejoinder to “Efficient statistical inference for a parallel study with missing data by using an exact method”.
Journal of biopharmaceutical statistics.
29(6):1174-1175
[DOI] 10.1080/10543406.2019.1641819.
[PMID] 31314673.
2019
The Relations Among Depression, Cognition, and Brain Volume in Professional Boxers: A Preliminary Examination Using Brief Clinical Measures.
The Journal of head trauma rehabilitation.
34(6):E29-E39
[DOI] 10.1097/HTR.0000000000000495.
[PMID] 31033751.
2019
Trends and Related Factors of Cannabis-Associated Emergency Department Visits in the United States: 2006-2014.
Journal of addiction medicine.
13(3):193-200
[DOI] 10.1097/ADM.0000000000000479.
[PMID] 30418337.
2019
Two-stage optimal designs with survival endpoint when the follow-up time is restricted
BMC Medical Research Methodology.
19(1)
[DOI] 10.1186/s12874-019-0696-x.
[PMID] 30943896.
2019
Two‐Stage Bagging Pruning for Reducing the Ensemble Size and Improving the Classification Performance
Mathematical Problems in Engineering.
2019(1)
[DOI] 10.1155/2019/8906034.
2018
Accurate unconditional p-values for a two-arm study with binary endpoints.
Journal of statistical computation and simulation.
88(6):1200-1210
[DOI] 10.1080/00949655.2018.1425690.
[PMID] 31080301.
2018
Biomarkers of Cognitive Impairment: Brain Cortical Thickness, Volumetrics, and Cerebrospinal Fluid.
Alzheimer disease and associated disorders.
32(3):255-257
[DOI] 10.1097/WAD.0000000000000226.
[PMID] 29189303.
2018
Biomedical informatics applications for precision management of neurodegenerative diseases.
Alzheimer's & dementia (New York, N. Y.).
4:357-365
[DOI] 10.1016/j.trci.2018.03.007.
[PMID] 30175230.
2018
Determining sample size for a binary diagnostic test in the presence of verification bias.
Journal of biopharmaceutical statistics.
28(6):1193-1202
[DOI] 10.1080/10543406.2018.1452029.
[PMID] 29553878.
2018
Exact confidence limits for the probability of response in two-stage designs.
Statistics.
52(5):1086-1095
[DOI] 10.1080/02331888.2018.1469023.
[PMID] 30906095.
2018
Exact confidence limits for the response rate in two-stage designs with over- or under-enrollment in the second stage.
Statistical methods in medical research.
27(4):1045-1055
[DOI] 10.1177/0962280216650918.
[PMID] 27389669.
2018
Longitudinal Performance of Plasma Neurofilament Light and Tau in Professional Fighters: The Professional Fighters Brain Health Study.
Journal of neurotrauma.
35(20):2351-2356
[DOI] 10.1089/neu.2017.5553.
[PMID] 29609512.
2018
Nevada’s Medicaid expansion and admissions for ambulatory care-sensitive conditions.
The American journal of managed care.
24(5):e157-e163
[PMID] 29851447.
2018
Optimal inference for Simon’s two-stage design with over or under enrollment at the second stage.
Communications in statistics: Simulation and computation.
47(4):1157-1167
[DOI] 10.1080/03610918.2017.1307398.
[PMID] 31097866.
2018
Sample size calculation for agreement between two raters with binary endpoints using exact tests.
Statistical methods in medical research.
27(7):2132-2141
[DOI] 10.1177/0962280216676854.
[PMID] 27856958.
2018
Sample size determination for a matched-pairs study with incomplete data using exact approach.
The British journal of mathematical and statistical psychology.
71(1):60-74
[DOI] 10.1111/bmsp.12107.
[PMID] 28664985.
2018
Sex Moderates the Impact of Diagnosis and Amyloid PET Positivity on Hippocampal Subfield Volume.
Journal of Alzheimer's disease : JAD.
64(1):79-89
[DOI] 10.3233/JAD-180028.
[PMID] 29865063.
2018
Statistical advances in clinical trials and clinical research.
Alzheimer's & dementia (New York, N. Y.).
4:366-371
[DOI] 10.1016/j.trci.2018.04.006.
[PMID] 30175231.
2017
A better confidence interval for the sensitivity at a fixed level of specificity for diagnostic tests with continuous endpoints.
Statistical methods in medical research.
26(1):268-279
[DOI] 10.1177/0962280214544313.
[PMID] 25049287.
2017
Boundary problem in Simon’s two-stage clinical trial designs.
Journal of biopharmaceutical statistics.
27(1):25-33
[DOI] 10.1080/10543406.2016.1148716.
[PMID] 26881325.
2017
Comments on ‘Two‐sample binary phase 2 trials with low type I error and low sample size’
Statistics in Medicine.
36(21):3437-3438
[DOI] 10.1002/sim.7359.
2017
Efficient confidence limits for adaptive one-arm two-stage clinical trials with binary endpoints.
BMC medical research methodology.
17(1)
[DOI] 10.1186/s12874-017-0297-5.
[PMID] 28166741.
2017
Exact one-sided confidence limits for Cohen’s kappa as a measurement of agreement.
Statistical methods in medical research.
26(2):615-632
[DOI] 10.1177/0962280214552881.
[PMID] 25288510.
2017
Exact unconditional sample size determination for paired binary data (letter commenting: J Clin Epidemiol. 2015;68:733-739)
Journal of Clinical Epidemiology.
84:188-190
[DOI] 10.1016/j.jclinepi.2016.07.018.
2017
Fisher’s exact approach for post hoc analysis of a chi-squared test
PLOS ONE.
12(12)
[DOI] 10.1371/journal.pone.0188709.
[PMID] 29261690.
2017
Gaussian network model can be enhanced by combining solvent accessibility in proteins.
Scientific reports.
7(1)
[DOI] 10.1038/s41598-017-07677-9.
[PMID] 28790346.
2017
Pharmacy Residency School-wide Match Rates and Modifiable Predictors in ACPE-accredited Colleges and Schools of Pharmacy.
American journal of pharmaceutical education.
81(10)
[DOI] 10.5688/ajpe6109.
[PMID] 29367773.
2016
Changes in Inflammatory and Bone Turnover Markers After Periodontal Disease Treatment in Patients With Diabetes.
The American journal of the medical sciences.
351(6):589-94
[DOI] 10.1016/j.amjms.2016.02.004.
[PMID] 27238921.
2016
Exact p-values for Simon’s two-stage designs in clinical trials.
Statistics in biosciences.
8(2):351-357
[DOI] 10.1007/s12561-016-9152-1.
[PMID] 28003856.
2016
Identification of Hot Spots in Protein Structures Using Gaussian Network Model and Gaussian Naive Bayes.
BioMed research international.
2016
[PMID] 27882325.
2016
Minimax and admissible adaptive two-stage designs in phase II clinical trials.
BMC medical research methodology.
16
[DOI] 10.1186/s12874-016-0194-3.
[PMID] 27485595.
2016
Optimal adaptive two-stage designs for early phase II clinical trials.
Statistics in medicine.
35(8):1257-66
[DOI] 10.1002/sim.6794.
[PMID] 26526165.
2016
Racial and Insurance Status Disparities in Patient Safety Indicators among Hospitalized Patients.
Ethnicity & disease.
26(3):443-52
[DOI] 10.18865/ed.26.3.443.
[PMID] 27440986.
2016
Sample size calculation based on efficient unconditional tests for clinical trials with historical controls.
Journal of biopharmaceutical statistics.
26(2):240-9
[DOI] 10.1080/10543406.2014.1000545.
[PMID] 25551261.
2016
Unconditional tests for comparing two ordered multinomials.
Statistical methods in medical research.
25(1):241-54
[DOI] 10.1177/0962280212450957.
[PMID] 22700600.
2015
Efficient Noninferiority Testing Procedures for Simultaneously Assessing Sensitivity and Specificity of Two Diagnostic Tests.
Computational and mathematical methods in medicine.
2015
[DOI] 10.1155/2015/128930.
[PMID] 26366190.
2015
Exact confidence intervals for the relative risk and the odds ratio.
Biometrics.
71(4):985-95
[DOI] 10.1111/biom.12360.
[PMID] 26228945.
2015
Homogeneity test for correlated binary data.
PloS one.
10(4)
[DOI] 10.1371/journal.pone.0124337.
[PMID] 25897962.
2015
Longitudinal trends in asthma health care use in Southern Nevada.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.
114(1):70-72.e2
[DOI] 10.1016/j.anai.2014.10.010.
[PMID] 25457866.
2015
Unconditional tests for association in 2 × 2 contingency tables in the total sum fixed design
Statistica Neerlandica.
69(1):67-83
[DOI] 10.1111/stan.12047.
2014
A new powerful nonparametric rank test for ordered alternative problem.
PloS one.
9(11)
[DOI] 10.1371/journal.pone.0112924.
[PMID] 25405757.
2014
Exact approaches for testing hypotheses based on the intra-class kappa coefficient.
Statistics in medicine.
33(17):2998-3012
[DOI] 10.1002/sim.6135.
[PMID] 24634280.
2014
Powerful exact unconditional tests for agreement between two raters with binary endpoints.
PloS one.
9(5)
[DOI] 10.1371/journal.pone.0097386.
[PMID] 24837970.
2014
The effect of a trail use intervention on urban trail use in Southern Nevada
Preventive Medicine.
67:S17-S20
[DOI] 10.1016/j.ypmed.2014.04.027.
2013
A note on exact conditional and unconditional tests for Hardy-Weinberg equilibrium.
Human heredity.
76(1):10-7
[DOI] 10.1159/000353205.
[PMID] 23921792.
2013
Randomized two-stage Phase II clinical trial designs based on Barnard’s exact test.
Journal of biopharmaceutical statistics.
23(5):1081-90
[DOI] 10.1080/10543406.2013.813525.
[PMID] 23957517.
2013
Some tests for detecting trends based on the modified Baumgartner-Weiβ-Schindler statistics.
Computational statistics & data analysis.
57(1):246-261
[PMID] 27030785.
2012
An efficient and exact approach for detecting trends with binary endpoints.
Statistics in medicine.
31(2):155-64
[DOI] 10.1002/sim.4411.
[PMID] 22162106.
2012
Exact two-stage designs for phase II activity trials with rank-based endpoints.
Contemporary clinical trials.
33(2):332-41
[DOI] 10.1016/j.cct.2011.10.008.
[PMID] 22074983.
2012
Two-stage k-sample designs for the ordered alternative problem.
Pharmaceutical statistics.
11(4):287-94
[DOI] 10.1002/pst.1499.
[PMID] 22408050.
Grants
May 2024
ACTIVE
ACTIVE MIND: An adaptive clinical trial of cognitive training to improve function and delay dementia
Role: Co-Investigator
Funding: UNIV OF ALABAMA BIRMINGHAM
via NATL INST OF HLTH NIA
Apr 2024
ACTIVE
Proteolysis targeting chimera against nuclear receptor NR4A1 for melanoma therapy
Role: Co-Investigator
Funding: NATL INST OF HLTH NCI
Mar 2024
ACTIVE
Patient and Clinician Perspectives on Spinal Manipulative Therapy
Role: Co-Investigator
Funding: AMER ACAD ORTHOPAEDIC MANUAL PHYS THERAP
Sep 2023
ACTIVE
Application of deep learning and novel survival models to predict MCI-to-AD dementia progression
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
May 2023
ACTIVE
Critical Time Window for Rehabilitation After Incomplete Spinal Cord Injury: Early vs Late Locomotor Training
Role: Principal Investigator
Funding: RIC dba SHIRLEY RYAN ABILITYLAB
via US DEPT OF DEFENSE
Mar 2023
ACTIVE
Pterygopalatine Fossa (PPF) Block as an Opioid Sparing Treatment for Acute Headache in Aneurysmal Subarachnoid Hemorrhage
Role: Co-Investigator
Funding: NATL INST OF HLTH NINDS
Jan 2023
ACTIVE
Exploring novel therapeutic strategies for combinatory therapy to treat renal clear cell carcinomas
Role: Co-Investigator
Funding: NATL INST OF HLTH NCI
Sep 2022
ACTIVE
Breathing Low Oxygen to Enhance Spinal Stimulation Training and Functional Recovery in Persons with Chronic SCI: The BO2ST Trial
Role: Principal Investigator
Funding: SPAULDING REHABILITATION HOSPITAL
via US ARMY MED RES ACQUISITION
Sep 2022
– Apr 2024
ACTIVE MIND: An adaptive clinical trial of cognitive training to improve function and delay dementia
Role: Co-Investigator
Funding: UNIV OF SOUTH FLORIDA
via NATL INST OF HLTH NIA
May 2021
– Jan 2024
Adaptive randomized designs for cancer clinical trials by using integer algorithms and exact Monte Carlo methods
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
May 2021
ACTIVE
Alzheimer's Disease: New Trial Designs for Emerging Challenges
Role: Principal Investigator
Funding: NATL INST OF HLTH NIA
Education
Ph.D., Biostatistics
2011
·
University at Buffalo
M.A., Biostatistics
2009
·
University at Buffalo
M.S., Bioinformatics
2007
·
Nankai University
B.S., Mathematics
2004
·
Nankai University
Contact Details
Phones:
- Business:
- (352) 294-5934
Emails:
- Business:
- gshan@ufl.edu
Addresses:
- Business Mailing:
-
Box 117450
GAINESVILLE FL 32611