Natalie E Dean

Natalie E Dean,

Assistant Professor

Department: PHHP-COM BIOSTATISTICS
Business Phone: (352) 294-1945
Business Email: nataliedean@ufl.edu

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-3884-0921

Publications

2021
COVID vaccination studies: plan now to pool data, or be bogged down in confusion.
Nature. 591(7849) [DOI] 10.1038/d41586-021-00563-5. [PMID] 33658668.
2021
Covid-19 Vaccine Effectiveness and the Test-Negative Design.
The New England journal of medicine. [DOI] 10.1056/NEJMe2113151. [PMID] 34496195.
2021
Cryptic transmission of SARS-CoV-2 and the first COVID-19 wave in Europe and the United States.
medRxiv : the preprint server for health sciences. [DOI] 10.1101/2021.03.24.21254199. [PMID] 33791745.
2021
Factors Associated With Household Transmission of SARS-CoV-2: An Updated Systematic Review and Meta-analysis.
JAMA network open. 4(8) [DOI] 10.1001/jamanetworkopen.2021.22240. [PMID] 34448865.
2021
Hospital admissions due to COVID-19 in Scotland after one dose of vaccine.
Lancet (London, England). 397(10285):1601-1603 [DOI] 10.1016/S0140-6736(21)00765-0. [PMID] 33901421.
2021
Household transmission of SARS-CoV-2 and risk factors for susceptibility and infectivity in Wuhan: a retrospective observational study.
The Lancet. Infectious diseases. 21(5):617-628 [DOI] 10.1016/S1473-3099(20)30981-6. [PMID] 33476567.
2021
SARS-CoV-2 shifting transmission dynamics and hidden reservoirs potentially limit efficacy of public health interventions in Italy.
Communications biology. 4(1) [DOI] 10.1038/s42003-021-02025-0. [PMID] 33883675.
2021
Statistical successes and failures during the COVID-19 pandemic: Comments on Ellenberg and Morris.
Statistics in medicine. 40(11):2515-2517 [DOI] 10.1002/sim.8934. [PMID] 33963583.
2021
The Usefulness of the Test-Positive Proportion of Severe Acute Respiratory Syndrome Coronavirus 2 as a Surveillance Tool.
American journal of epidemiology. 190(7):1396-1405 [DOI] 10.1093/aje/kwab023. [PMID] 33576387.
2021
Theoretical Framework for Retrospective Studies of the Effectiveness of SARS-CoV-2 Vaccines.
Epidemiology (Cambridge, Mass.). 32(4):508-517 [DOI] 10.1097/EDE.0000000000001366. [PMID] 34001753.
2021
Using simulated infectious disease outbreaks to inform site selection and sample size for individually randomized vaccine trials during an ongoing epidemic.
Clinical trials (London, England). [DOI] 10.1177/17407745211028898. [PMID] 34218667.
2020
Accumulating evidence from randomized clinical trials across outbreaks
New England Journal of Medicine.
2020
Aggregating data from COVID-19 trials.
Science (New York, N.Y.). 368(6496):1198-1199 [DOI] 10.1126/science.abc8993. [PMID] 32527823.
2020
COVID-19 Clinical Trials: A Teachable Moment for Improving Our Research Infrastructure and Relevance.
Annals of internal medicine. 173(8):652-653 [DOI] 10.7326/M20-2959. [PMID] 32543881.
2020
Creating a Framework for Conducting Randomized Clinical Trials during Disease Outbreaks.
The New England journal of medicine. 382(14):1366-1369 [DOI] 10.1056/NEJMsb1905390. [PMID] 32242365.
2020
Ensemble forecast modeling for the design of COVID-19 vaccine efficacy trials.
Vaccine. 38(46):7213-7216 [DOI] 10.1016/j.vaccine.2020.09.031. [PMID] 33012602.
2020
Estimating the establishment of local transmission and the cryptic phase of the COVID-19 pandemic in the USA.
medRxiv : the preprint server for health sciences. [DOI] 10.1101/2020.07.06.20140285. [PMID] 32676609.
2020
High levels of HIV drug resistance among adults failing second-line antiretroviral therapy in Namibia.
Medicine. 99(37) [DOI] 10.1097/MD.0000000000021661. [PMID] 32925712.
2020
Household secondary attack rate of COVID-19 and associated determinants in Guangzhou, China: a retrospective cohort study.
The Lancet. Infectious diseases. 20(10):1141-1150 [DOI] 10.1016/S1473-3099(20)30471-0. [PMID] 32562601.
2020
Household Secondary Attack Rate of COVID-19 and Associated Determinants.
medRxiv : the preprint server for health sciences. [DOI] 10.1101/2020.04.11.20056010. [PMID] 32511590.
2020
Household transmission of SARS-CoV-2: a systematic review and meta-analysis of secondary attack rate.
medRxiv : the preprint server for health sciences. [DOI] 10.1101/2020.07.29.20164590. [PMID] 32766596.
2020
Household Transmission of SARS-CoV-2: A Systematic Review and Meta-analysis.
JAMA network open. 3(12) [DOI] 10.1001/jamanetworkopen.2020.31756. [PMID] 33315116.
2020
Modeling the impact of social distancing, testing, contact tracing and household quarantine on second-wave scenarios of the COVID-19 epidemic.
medRxiv : the preprint server for health sciences. [DOI] 10.1101/2020.05.06.20092841. [PMID] 32511536.
2020
Modelling the impact of testing, contact tracing and household quarantine on second waves of COVID-19.
Nature human behaviour. 4(9):964-971 [DOI] 10.1038/s41562-020-0931-9. [PMID] 32759985.
2020
Preventing a Secondary Epidemic of Lost Early Career Scientists. Effects of COVID-19 Pandemic on Women with Children.
Annals of the American Thoracic Society. 17(11):1366-1370 [DOI] 10.1513/AnnalsATS.202006-589IP. [PMID] 32667850.
2020
Temporal Confounding in the Test-Negative Design.
American journal of epidemiology. 189(11):1402-1407 [DOI] 10.1093/aje/kwaa084. [PMID] 32415834.
2020
The TIRS trial: protocol for a cluster randomized controlled trial assessing the efficacy of preventive targeted indoor residual spraying to reduce Aedes-borne viral illnesses in Merida, Mexico.
Trials. 21(1) [DOI] 10.1186/s13063-020-04780-7. [PMID] 33032661.
2020
Two-stage adaptive enrichment design for testing an active factor.
Journal of biopharmaceutical statistics. 30(1):18-30 [DOI] 10.1080/10543406.2019.1609015. [PMID] 31135263.
2020
Understanding COVID-19 vaccine efficacy.
Science (New York, N.Y.). 370(6518):763-765 [DOI] 10.1126/science.abe5938. [PMID] 33087460.
2019
An online decision tree for vaccine efficacy trial design during infectious disease epidemics: The InterVax-Tool.
Vaccine. 37(31):4376-4381 [DOI] 10.1016/j.vaccine.2019.06.019. [PMID] 31242963.
2019
Design of vaccine efficacy trials during public health emergencies.
Science translational medicine. 11(499) [DOI] 10.1126/scitranslmed.aat0360. [PMID] 31270270.
2019
Provincial and national prevalence estimates of transmitted HIV-1 drug resistance in South Africa measured using two WHO-recommended methods.
Antiviral therapy. 24(3):203-210 [DOI] 10.3851/IMP3294. [PMID] 30741163.
2019
RE: “MEASUREMENT OF VACCINE DIRECT EFFECTS UNDER THE TEST-NEGATIVE DESIGN”.
American journal of epidemiology. 188(4):806-810 [DOI] 10.1093/aje/kwz019. [PMID] 30689690.
2018
Avian Influenza A Virus Infection among Workers at Live Poultry Markets, China, 2013-2016.
Emerging infectious diseases. 24(7):1246-1256 [DOI] 10.3201/eid2407.172059. [PMID] 29912708.
2018
DESIGN OF VACCINE TRIALS DURING OUTBREAKS WITH AND WITHOUT A DELAYED VACCINATION COMPARATOR.
The annals of applied statistics. 12(1):330-347 [DOI] 10.1214/17-AOAS1095. [PMID] 29606991.
2018
Quantifying the risk of local Zika virus transmission in the contiguous US during the 2015-2016 ZIKV epidemic.
BMC medicine. 16(1) [DOI] 10.1186/s12916-018-1185-5. [PMID] 30336778.
2017
Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!).
Lancet (London, England). 389(10068):505-518 [DOI] 10.1016/S0140-6736(16)32621-6. [PMID] 28017403.
2017
Ring vaccination with rVSV-ZEBOV under expanded access in response to an outbreak of Ebola virus disease in Guinea, 2016: an operational and vaccine safety report.
The Lancet. Infectious diseases. 17(12):1276-1284 [DOI] 10.1016/S1473-3099(17)30541-8. [PMID] 29033032.
2017
Spread of Zika virus in the Americas.
Proceedings of the National Academy of Sciences of the United States of America. 114(22):E4334-E4343 [DOI] 10.1073/pnas.1620161114. [PMID] 28442561.
2017
The public health value of vaccines beyond efficacy: methods, measures and outcomes.
BMC medicine. 15(1) [DOI] 10.1186/s12916-017-0911-8. [PMID] 28743299.
2016
Assessment of the World Health Organization’s HIV Drug Resistance Early Warning Indicators in Main and Decentralized Outreach Antiretroviral Therapy Sites in Namibia.
PloS one. 11(12) [DOI] 10.1371/journal.pone.0166649. [PMID] 27906995.
2016
Containing Ebola at the Source with Ring Vaccination.
PLoS neglected tropical diseases. 10(11) [DOI] 10.1371/journal.pntd.0005093. [PMID] 27806049.
2016
Spatiotemporal dynamics of the Ebola epidemic in Guinea and implications for vaccination and disease elimination: a computational modeling analysis.
BMC medicine. 14(1) [DOI] 10.1186/s12916-016-0678-3. [PMID] 27600737.
2016
The epidemiology and transmissibility of Zika virus in Girardot and San Andres island, Colombia, September 2015 to January 2016.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 21(28) [DOI] 10.2807/1560-7917.ES.2016.21.28.30283. [PMID] 27452806.
2016
Transmissibility and Pathogenicity of Ebola Virus: A Systematic Review and Meta-analysis of Household Secondary Attack Rate and Asymptomatic Infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 62(10):1277-1286 [DOI] 10.1093/cid/ciw114. [PMID] 26932131.
2016
Transmission dynamics of Ebola virus disease and intervention effectiveness in Sierra Leone.
Proceedings of the National Academy of Sciences of the United States of America. 113(16):4488-93 [DOI] 10.1073/pnas.1518587113. [PMID] 27035948.
2016
Urinary incontinence persisting after childbirth: extent, delivery history, and effects in a 12-year longitudinal cohort study.
BJOG : an international journal of obstetrics and gynaecology. 123(6):1022-9 [DOI] 10.1111/1471-0528.13395. [PMID] 25846816.
2015
Ebola vaccination – Authors’ reply.
Lancet (London, England). 386(10012) [DOI] 10.1016/S0140-6736(15)00951-4. [PMID] 26738716.
2015
Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial.
Lancet (London, England). 386(9996):857-66 [DOI] 10.1016/S0140-6736(15)61117-5. [PMID] 26248676.
2015
Evaluating Confidence Interval Methods for Binomial Proportions in Clustered Surveys
Journal of Survey Statistics and Methodology. 3(4):484-503
2015
Factors associated with the transfer of pediatric patients with supracondylar humerus fractures to a level I pediatric trauma center
. 79(8):461-466
2015
Factors Associated with the Transfer of Pediatric Patients with Supracondylar Humerus Fractures to a Level I Pediatric Trauma Center.
Connecticut medicine. 79(8):461-6 [PMID] 26506677.
View on: PubMed
2015
The ring vaccination trial: a novel cluster randomised controlled trial design to evaluate vaccine efficacy and effectiveness during outbreaks, with special reference to Ebola
British Medical Journal. 351
2013
Faecal incontinence persisting after childbirth: a 12 year longitudinal study.
BJOG : an international journal of obstetrics and gynaecology. 120(2):169-179 [DOI] 10.1111/1471-0528.12039. [PMID] 23190303.
2013
Malnutrition in the first year of life and personality at age 40
The Journal of Child Psychology and Psychiatry. 54(8):911-919 [DOI] 10.1111/jcpp.12066. [PMID] 23488644.
2010
Early childhood malnutrition predicts depressive symptoms at ages 11-17
The Journal of Child Psychology and Psychiatry. 51(7):789-798 [DOI] 10.1111/j.1469-7610.2010.02208.x. [PMID] 20331492.
2001
Contribution of endogenously expressed Trp1 to a Ca2+-selective, store-operated Ca2+ entry pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 15(10):1704-1710 [PMID] 11481220.
View on: PubMed

Grants

Sep 2020 ACTIVE
Mathematical and Statistical Methods for the Control of Global Infectious Disease Threats
Role: Project Manager
Funding: NATL INST OF HLTH NIAID
Apr 2020 ACTIVE
RAPID: Dynamic Identification of SARS-COV-2 Transmission Epicenters in Presence of Spatial Heterogeneity (COV-DYNAMITE)
Role: Project Manager
Funding: NATL SCIENCE FOU
Apr 2020 ACTIVE
Quantifying the Epidemiological Impact of Targeted Indoor Residual Spraying on Aedes-borne Diseases
Role: Co-Investigator
Funding: EMORY UNIV via NATL INST OF HLTH NIAID
Aug 2018 – Jul 2021
Design and Analysis of Vaccine Trials for Emerging Infectious Disease Threats
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAID
Jul 2017 – Sep 2017
To provide technical support to the WHO Blueprint and develop a guidance document for vaccine clinical evaluation in Public Health Emergencies
Role: Principal Investigator
Funding: WORLD HLTH ORGANIZATION
Aug 2016 – Jan 2017
Dengue Vaccine Seroprevalence Surveys
Role: Principal Investigator
Funding: WORLD HLTH ORGANIZATION

Teaching Profile

Courses Taught
2020-2021
PHC7980 Research for Doctoral Dissertation
2019,2021
PHC6905 Independent Study
2018-2021
PHC7979 Advanced Research
2019-2020
PHC6059 Introduction to Applied Survival Analysis
2017-2018
PHC6937 Special Topics in Public Health
2017
STA6177 Applied Survival Analysis
2016
PHC4094 Introduction to Biostatistics for Health Science and Public Health

Contact Details

Phones:
Business:
(352) 294-1945
Emails: